Publications:
Pubmed Records Google Scholar Profile
16. *Eckle VS, *Shcheglovitov A, *Vitko I, Dey D, Yap CC, Winckler B, Perez-Reyes E (2014) Mechanisms by which CACNA1H mutations found in epilepsy patients increase seizure susceptibility. Journal of Physiology 592(Pt 4): 795–809
(*equally contributing authors) pdf
15. Shcheglovitov A, Shcheglovitova O, Yazawa M, Portmann T, Shu R, Sebastiano V, Krawisz A, Froehlich W, Bernstein JA, Hallmayer J, Dolmetsch RE (2013) Shank3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients. Nature 503(7475): 267–71 pdf suppl
Featured in: Cell (Dec 13, 2013); Faculty of 1000
14. Krey JF, Paşca SP, Shcheglovitov A, Yazawa M, Schwemberger R, Rasmusson R, Dolmetsch RE (2012) Timothy Syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons. Nature Neuroscience 16(2): 201–9 pdf
13. *Shcheglovitov A, Vitko I, Lazarenko R, Orestes P, Todorovic SM, *Perez-Reyes E (2012) Molecular and biophysical basis of glutamate and trace metal modulation of voltage-gated Cav2.3 calcium channels. Journal of General Physiology 139(3): 219–34
(*corresponding authors) pdf
12. Paşca SP, Portmann T, Voineagu I, Yazawa M, Shcheglovitov A, Paşca AM, Cord B, Palmer TD, Chikahisa S, Seiji N, Bernstein JA, Hallmayer J, Geschwind DH, Dolmetsch RE (2011) Using iPS cell-derived neurons to uncover cellular phenotypes in patients with Timothy Syndrome. Nature Medicine 17(12): 1657–62 pdf
Featured in: Nat Med (Dec 6, 2011); Nat Rev Neurosci (Dec 20, 2011); Faculty of 1000
11. *Yoo AS, *Sun AX, *Li L, *Shcheglovitov A, Portmann T, Li Y, Lee-Messer C, Dolmetsch RE, Tsien RW, Crabtree GR (2011) MicroRNA-mediated conversion of human fibroblasts to neurons. Nature 476(7359): 228–31
(*equally contributing authors) pdf
Featured in: Nature 476(7359); Faculty of 1000
10. Nguyen HN, Byers B, Cord B, Shcheglovitov A, Byrne J, Gujar P, Kee K, Schüle B, Dolmetsch RE, Langston W, Palmer TD, Reijo-Pera R (2011) LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress. Cell Stem Cell 8(3): 267–80
9. Park CY, Shcheglovitov A, Dolmetsch R (2010) The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels. Science 330(6000): 101–5
Featured in: Science 330(6000); Faculty of 1000;
8. *Shcheglovitov A, *Vitko I, Bidaud I, Baumgart JP, Navaro-Gonzalez MF, Grayson H, Lory P, Hill CE, Perez-Reyes E (2008) Alternative splicing within the I-II loop controls surface expression of T-type Cav3.1 calcium channels. FEBS Letters 582(27): 3765–70 (*equally contributing authors)
7. *Vitko I, *Shcheglovitov A, Baumgart JP, Arias-Olguin II, Murbartian J, Arias JM, Perez-Reyes E (2008) Orientation of the calcium channel β relative to the α12.2 subunit is critical for its regulation of channel activity. PLoS ONE 3(10): e3560
(*equally contributing authors)
6. Shcheglovitov A, Kostyuk P, Shuba Y (2007) Selectivity signatures of three isoforms of recombinant T-type Ca2+ channels. Biochimica et Biophysica Acta–Biomembranes 1768: 1406–19
5. Shcheglovitov AK, Shuba YM (2006) Sodium-calcium selectivity of cloned T-type calcium channels. Neurophysiology (Springer) 38(3): 183–92
4. Shcheglovitov AK, Boldyrev OI, Lyubanova OP, Shuba YM (2005) Peculiarity of recombinant T-type calcium channel selectivity for divalent cations. Neurophysiology (Springer) 37(4): 319–29
3. Dosenko VE, Lyubanova OP, Shcheglovitov AK, Boldyrev OI, Shuba YM (2005) Expression of low-voltage-activated (T-type) calcium channel genes in rat thalamic dorsolateral nucleus: onthogenetic aspect. Neurophysiology (Springer) 37(3): 201–6
2. *Shcheglovitov A, *Zhelay T, Vitko Y, Osipenko V, Perez-Reyes E, Kostyuk P, Shuba Y (2005) Contrasting the effects of nifedipine on subtypes of endogenous and recombinant T-type Ca2+ channels. Biochemical Pharmacology 69(5): 841–54
(*equally contributing authors)
1. Zhelay TI, Shcheglovitov AK (2004) Effects of nifedipine on voltage-regulated low-threshold Ca2+-channels in rat thalamic neurons. Neurophysiology (Springer) 36(3): 193–203
(*equally contributing authors) pdf
15. Shcheglovitov A, Shcheglovitova O, Yazawa M, Portmann T, Shu R, Sebastiano V, Krawisz A, Froehlich W, Bernstein JA, Hallmayer J, Dolmetsch RE (2013) Shank3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients. Nature 503(7475): 267–71 pdf suppl
Featured in: Cell (Dec 13, 2013); Faculty of 1000
14. Krey JF, Paşca SP, Shcheglovitov A, Yazawa M, Schwemberger R, Rasmusson R, Dolmetsch RE (2012) Timothy Syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons. Nature Neuroscience 16(2): 201–9 pdf
13. *Shcheglovitov A, Vitko I, Lazarenko R, Orestes P, Todorovic SM, *Perez-Reyes E (2012) Molecular and biophysical basis of glutamate and trace metal modulation of voltage-gated Cav2.3 calcium channels. Journal of General Physiology 139(3): 219–34
(*corresponding authors) pdf
12. Paşca SP, Portmann T, Voineagu I, Yazawa M, Shcheglovitov A, Paşca AM, Cord B, Palmer TD, Chikahisa S, Seiji N, Bernstein JA, Hallmayer J, Geschwind DH, Dolmetsch RE (2011) Using iPS cell-derived neurons to uncover cellular phenotypes in patients with Timothy Syndrome. Nature Medicine 17(12): 1657–62 pdf
Featured in: Nat Med (Dec 6, 2011); Nat Rev Neurosci (Dec 20, 2011); Faculty of 1000
11. *Yoo AS, *Sun AX, *Li L, *Shcheglovitov A, Portmann T, Li Y, Lee-Messer C, Dolmetsch RE, Tsien RW, Crabtree GR (2011) MicroRNA-mediated conversion of human fibroblasts to neurons. Nature 476(7359): 228–31
(*equally contributing authors) pdf
Featured in: Nature 476(7359); Faculty of 1000
10. Nguyen HN, Byers B, Cord B, Shcheglovitov A, Byrne J, Gujar P, Kee K, Schüle B, Dolmetsch RE, Langston W, Palmer TD, Reijo-Pera R (2011) LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress. Cell Stem Cell 8(3): 267–80
9. Park CY, Shcheglovitov A, Dolmetsch R (2010) The CRAC channel activator STIM1 binds and inhibits L-type voltage-gated calcium channels. Science 330(6000): 101–5
Featured in: Science 330(6000); Faculty of 1000;
8. *Shcheglovitov A, *Vitko I, Bidaud I, Baumgart JP, Navaro-Gonzalez MF, Grayson H, Lory P, Hill CE, Perez-Reyes E (2008) Alternative splicing within the I-II loop controls surface expression of T-type Cav3.1 calcium channels. FEBS Letters 582(27): 3765–70 (*equally contributing authors)
7. *Vitko I, *Shcheglovitov A, Baumgart JP, Arias-Olguin II, Murbartian J, Arias JM, Perez-Reyes E (2008) Orientation of the calcium channel β relative to the α12.2 subunit is critical for its regulation of channel activity. PLoS ONE 3(10): e3560
(*equally contributing authors)
6. Shcheglovitov A, Kostyuk P, Shuba Y (2007) Selectivity signatures of three isoforms of recombinant T-type Ca2+ channels. Biochimica et Biophysica Acta–Biomembranes 1768: 1406–19
5. Shcheglovitov AK, Shuba YM (2006) Sodium-calcium selectivity of cloned T-type calcium channels. Neurophysiology (Springer) 38(3): 183–92
4. Shcheglovitov AK, Boldyrev OI, Lyubanova OP, Shuba YM (2005) Peculiarity of recombinant T-type calcium channel selectivity for divalent cations. Neurophysiology (Springer) 37(4): 319–29
3. Dosenko VE, Lyubanova OP, Shcheglovitov AK, Boldyrev OI, Shuba YM (2005) Expression of low-voltage-activated (T-type) calcium channel genes in rat thalamic dorsolateral nucleus: onthogenetic aspect. Neurophysiology (Springer) 37(3): 201–6
2. *Shcheglovitov A, *Zhelay T, Vitko Y, Osipenko V, Perez-Reyes E, Kostyuk P, Shuba Y (2005) Contrasting the effects of nifedipine on subtypes of endogenous and recombinant T-type Ca2+ channels. Biochemical Pharmacology 69(5): 841–54
(*equally contributing authors)
1. Zhelay TI, Shcheglovitov AK (2004) Effects of nifedipine on voltage-regulated low-threshold Ca2+-channels in rat thalamic neurons. Neurophysiology (Springer) 36(3): 193–203